AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Passive Calf Stretching Therapy in Peripheral Artery Disease

RecruitingNAAges 40 Years - 85 YearsAllPenn State University
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to assess the effects of passive calf muscle stretching in patients diagnosed with peripheral artery disease (PAD). The main question it aims to answer are: 1. To determine if daily calf muscle stretching at home improves calf muscle and vascular health. 2. To determine if daily calf muscle stretching at home improves walking performance. Participants will use inflatable ankle splints for 30 minutes a day, 5 days a week for 4-weeks on both days and 4-weeks of no stretching.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Presence of PAD * Stable condition (PAD symptoms) for at least 3 months * Age 40-85 * Men and women who are not pregnant or nursing Exclusion Criteria: * Ischemic leg pain at rest; critical limb ischemia (ulceration or gangrene) * Any condition other than PAD that limits the ability to walk * Major surgery or lower extremity revascularization surgery in the past 6 months * Myocardial infarction within past 6 months or unstable angina * Severe lung disease (on supplemental oxygen or frequently use rescue inhalers) * Participants with non-compressible vessels (ABI \> 1.40) * Habitual exercise (30 minutes of continuous activity on 3 or more days per week) * Current tobacco smoker or use of nicotine-containing products * Pregnant or nursing women * History or ankle reconstruction or surgery Recent history (\<1 year) of injuries to the ankle, Achilles tendon, or feet * History of rheumatoid arthritis or other degenerative joint disease * Major medical illness treatment during the prior 12 months * Uncontrolled hypertension * Uncontrolled diabetes * Inability to walk on a treadmill at a slow pace (1.0 mile/hour)
๐Ÿ’Š

What it tests

  • Passive calf muscle stretching device
๐Ÿ“

Where

1 site
Penn State University
University Park, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy