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TANGO-LIVER Three Arm Nuclear Growth Observation in Liver Surgery

RecruitingNAAges 18 Years - 80 YearsAllMedical University of Warsaw
NCT06050200 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Liver resection is the treatment of choice in patients with malignant liver lesions. Unfortunately, the surgery is not always an option, as in same patients the future remnant liver (FRL) is too small to supply all the functions. Therefore, some additional methods have been proposed to increase the size of the FRL. The aim of this study is to compare the efficacy and safety of three methods of increasing the future remnant liver - Portal Vein Embolization (PVE) - embolization of one of the portal branches; Liver Vein Deprivation (LVD) - embolization both of the portal branch as well as the hepatic vein; and partial ALPPS (Associating Liver Partition and Portal vein Ligation for Staged hepatectomy) - ligation of portal vein branch with partial liver transection. The efficacy of those three methods will be assessed both by analyzing the volumetric increase (by computer tomography scans)

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📋 Eligibility rules (as published)
Inclusion Criteria: * age \>= 18 years * patients qualified for liver resection * future remnant liver \<30% of standard liver volume * written informed consent Exclusion Criteria: * liver cirrhosis * pregnancy * poor general health status or comorbidities excluding general anesthesia or hepatic resection * contraindications to iodine contrast agents
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What it tests

  • PVE
  • LVD
  • ALPPS
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Where

1 site
Second Department of Clinical Radiology
Warsaw, Poland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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