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Innovation for Small-scale Experiments: ReceptIVFity Test

RecruitingNAAges 18 Years - 42 YearsFemaleErasmus Medical Center
NCT06051201 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The ReceptIVFity acts as a timing-tool for prediction of optimal pregnancy chances and provides insight into the patient's current (two months after sampling) success rate of an IVF/IVF-ICSI treatment. Benefits of physician decision treatment in case of an unfavorable vaginal profile and a low chance of achieving a pregnancy include reducing unnecessary morbidity and treatment cycles, stress and disappointment, while increasing efficacy of the treatment and lowering the costs needed to achieve a pregnancy. The goal of this prospective, clinical non-invasive randomized controlled study, with an additional observational study arm (for women of non-European origin) in naïve IVF or IVF/ICSI patients is to evaluate the efficiency of Shared Decision Making compared to Physician Decision in terms of 1. the success probability of an IVF cycle, 2. the proportion of women with a successful pregn

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Naïve IVF or IVF/ICSI patients 2. Indication for an IVF or IVF-ICSI procedure. 3. 18 years \< age \< 43 years. 4. Willing to provide a vaginal swab with the ReceptIVFity test. 5. Willing to provide informed consent. Exclusion Criteria: 1. The use of hormonal contraceptives at the time of taking the test. 2. The use of antibiotic treatment at the time of taking the test. 3. Emergency IVF for cancer or other reasons. 4. Women with endometriosis pre-treated with an Gn-RH analogue. 5. Women having IVF for egg preservation reasons.
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What it tests

  • ReceptIVFity test (vaginal microbiome swab)
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Where

1 site
Erasmus University Medical Center
Rotterdam, Netherlands
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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