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Efficacy of Rehabilitation Using Action Observation and Muscle Stimulation in Post-stroke Patients.

RecruitingNAAges 18 Years - anyAllFondazione Don Carlo Gnocchi ETS
NCT06055569 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Stroke is the third most common cause of disability worldwide and leads to upper limb motor disease in more than half of people affected. Recent data demonstrate that upper limb rehabilitation can be pursued using techniques such as the observation of action (Action Observation Therapy - AOT) or the stimulation of limb musculature using surface electrodes (Neuromuscular Electrical Stimulation - NMES). To date, no rehabilitation studies used both the treatments (AOT-NMES) for the rehabilitation of upper limb after stroke. The goal of this clinical trial is to study the efficacy of this combined approach (AOT-NMES) in people who developed upper limb motor impairment after stroke. The main question this study aims to answer is if the rehabilitation performed using both action observation and neuromuscular stimulation has an higher efficacy than the use of AOT alone and higher than the o

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age over 18 years; * Upper arm motor impairment after unilateral stroke as verified by MRI or CT; * Two weeks up to 6 months after stroke; * Grading of upper arm motor impairment\>2 at Medical Research Council scale (MRC). Exclusion Criteria: * Neurological/orthopedic issues that would interfere with upper limb exercises; * Presence of any medical condition that represents a contraindication to Magnetic Resonance Imaging (MRI) examination or to Transcranial Magnetic Stimulation (TMS); * Presence of dermatologic issues that will interfere with neuromuscular stimulator; * Presence of electronic subcutaneous implants; * Presence of peripheral neuropathy; * Epilepsy; * Pregnancy; * Presence of severe cognitive impairment, including language comprehension detected during the neurological evaluation.
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What it tests

  • Rehabilitation protocol: AOT+NMES
  • Rehabilitation protocol: Action Observation Therapy (AOT)
  • Observation of motor-neutral stimuli (MNO)
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Where

1 site
IRCCS Fondazione Don Carlo Gnocchi
Milan, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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