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Potassium, Hydration, Cardiovascular, and Kidney Study (PHACKs)

RecruitingNAAges 18 Years - 30 YearsAllAuburn University
NCT06062017 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Compared with White Adults, Non-Hispanic Black Adults are at an elevated risk of developing cardiovascular disease (CVD) and end stage chronic-kidney disease (CKD), two of the leading causes of death in the United States. Inadequate hydration status is associated with risk factors for both CVD and CKD. Prior data show that Black individuals are less likely to be adequately hydrated when compared with their White counterparts. Further, socioeconomic factors have been shown to influence hydration practices. Inadequate hydration influences certain hormones that regulate blood volume and impact blood pressure, but increasing potassium intake may provide some positive effects on normalizing these hormones and blood pressure. Black adults, in particular, are more likely to consume less potassium, have inadequate hydration, and tend to have higher blood pressure. As such, there is a critical ne

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📋 Eligibility rules (as published)
Inclusion Criteria: * Between the ages of 18-30 years * Resting blood pressure no higher than 150/90 mmHg * BMI below 35 kg/m2 * Free of any metabolic disease (e.g., diabetes) kidney disease, pulmonary disorders (e.g., COPD), cardiovascular disease (peripheral vascular, cardiac, or cerebrovascular), no autoimmune diseases, and no history of cancer. Exclusion Criteria: * Have any precluding medical conditions (i.e. hemophilia) or medication (Pradaxa, Eliquis, etc.) that prevent participants from giving blood. * Are currently pregnant or trying to become pregnant. * take any of the following medications that are contraindicated with potassium supplementation: * Renin-angiotensin-aldosterone system (RAAS) blockers: Candesartan , Eprosartan, Irbesartan, Losartan, Olmesartan, Telmisartan * Non -steroidal anti-inflammatory medications: Aspirin, Ibuprofen, Naproxen * Non-selective beta-blockers: Pindolol, Penbutolol, Oxprenolol, Propranolol, Nadolol, Sotalol, Timolol, Tertatolol * Calcineurin inhibitors: Cyclosporine * Heparin (or other blood thinning medications)
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What it tests

  • Water and Potassium supplementation
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Where

1 site
Kinesiology Building
Auburn, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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