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โ† Trials
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Effect of Transpulmonary MP on Prognosis of Patients With Severe ARDS Treated With VV-ECMO

Recruitingn/aAges 18 Years - 75 YearsAllBeijing Chao Yang Hospital
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In plain words

What the trial is, and whether it could suit you

Venovenous extracorporeal membrane oxygenation (VV-ECMO) is a salvage treatment for severe acute respiratory distress syndrome (ARDS). With the large-scale implementation of VV-ECMO in critical care medicine departments in China, significant progress has been made in treating severe ARDS. However, the patient mortality rate remains high. The pathophysiological essence of ARDS is an imbalance between the body's oxygen supply and demand, causing tissue and cell hypoxia, organ dysfunction, and even death. The VV-ECMO treatment process still requires mechanical ventilation assistance. However, inappropriate mechanical ventilation settings can lead to ventilator-related lung injury (VILI). In recent years, mechanical power has gradually attracted everyone's attention and is considered the cause of VILI. The transpulmonary mechanical power is more accurate to the energy directly performed to t

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Meet the diagnostic criteria of Berlin's definition for ARDS; 2. Receiving VV-ECMO support. Exclusion Criteria: 1. Patients had been on high pressure (Ppeak \>35 cm H2O) and a high fraction of inspired oxygen (FiO2\>0.8) ventilation for \>7 days; 2. Patients had a contraindication to heparinization; 3. Patients had an irreversible neurological injury; 4. Patients had severe chronic lung disease with life expectancy \<6 months.
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What it tests

  • Transpulmonary pressure
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Where

1 site
Beijing Chao-Yang Hospital
Beijing, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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