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Mass Vaccine and Drug Administration, Bangladesh

RecruitingPhase 4Ages 6 Months - anyAllUniversity of Oxford
NCT06068530 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

This is an open i.e. not blinded, cluster-randomised, controlled intervention study. The study will use a factorial design to estimate the protective effectiveness of mass drug administrations, mass vaccinations, combined mass vaccinations and drug administrations versus the current standard of care.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Current residence in a study village irrespective of permanence * Age 6 months and above (no upper age limit) * Written informed consent provided by participants (or a parent/guardian in case the participant is under 18 years old) Exclusion Criteria: * Pregnancy, plan to get pregnant, or breastfeeding. * Acute illness requiring intervention * A history of an adverse reaction to study drugs/vaccine and prior receipt of any other malaria vaccine or enrolment in another intervention trial.
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What it tests

  • DHA/piperaquine and a SLD-PQ
  • Study vaccine R21/Matrix-Mโ„ข
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Where

2 sites
Alikadam Upazila Health Complex
Bฤndarban, Bangladesh
Lama Upazila Health Complex
Lฤma, Bangladesh
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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