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Effect of Lactobacillus Johnsonii or White Pomegranate Extract on the Vaginal Health

RecruitingNAAges 20 Years - 45 YearsFemaleChung Shan Medical University
NCT06069531 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to explore the effect of Lactobacillus johnsonii and white pomegranate extract on female bacterial status, it aims to answer are: * Evaluate Lactobacillus johnsonii TCI250 probiotics or white pomegranate extract in regulating female vaginal bacteria and improving vaginal health. * Evaluate Lactobacillus johnsonii TCI250 probiotics or white pomegranate extract in regulating inflammation. Participants will be randomly assigned to placebo (n = 50), probiotic heat-killed Lactobacillus johnsonii TCI250 group (n = 50) and white pomegranate extract group (n = 50) for 8 weeks. Researchers will compare the vaginal flora and inflammation.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Females aged 20-45 2. Nugent score ≥ 4 3. Menstrual cycle of 28-60 days Exclusion Criteria: 1. Pregnant or lactating women 2. Antibiotic usage 3. Other reproductive-related inflammatory diseases (e.g., candidiasis, gonorrhea, chlamydia infection) 4. Allergy to probiotics or White Pomegranate-related components
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What it tests

  • Lactobacillus johnsonii, Placebo Comparator: White pomegranate extract
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Where

1 site
Chung Shan Medical University Hospital
Taichung, Taiwan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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