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Comparative Study Between (FC-SEMS) and (PC-SEMS) in the Palliation of Dysphagia Due to Malignant Neoplasm of Esophagus.

RecruitingNAAges 18 Years - anyAllInstituto do Cancer do Estado de São Paulo
NCT06070376 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Esophageal cancer is the seventh most common type of cancer in the world, with an estimated global incidence of 604,100 new cases per year. The main symptom of esophageal cancer is dysphagia, associated or not with weight loss. Unfortunately, due to asymptomatic presentation in the early stages, more than half of patients are diagnosed in advanced stages of the disease, becoming ineligible for treatment with curative intent. In this sense, chemotherapy and radiotherapy are the pillars of palliative treatment, often regressing the injury and improving symptoms. However, some patients persist with dysphagia. In this scenario, esophageal prostheses are one of the main tools in the palliative treatment of esophageal cancer dysphagia, obtaining rapid and lasting relief of dysphagia. This study aims to compare fully covered (FC-SEMS) and partially covered (PC-SEMS) esophageal prostheses in thi

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with advanced malignant neoplasm of the esophagus, whether or not undergoing chemotherapy or radiotherapy; * Dysphagia score greater than 2 or presence of malignant esophagorespiratory fistula; * Indication of palliation of dysphagia through the placement of esophageal prostheses in a multidisciplinary meeting. Exclusion Criteria: * Patients under 18 years; * Extraesophageal neoplasms; * Lesions with longitudinal extension less than 30 mm; * Previous treatment with esophageal prosthesis; * Tumors easily transposed to standard endoscope (9.8mm).
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What it tests

  • Fully Covered Esophageal Prosthesis (FC-SEMS)
  • Partially Covered Esophageal Prosthesis (PC-SEMS)
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Where

1 site
Instituto do Câncer do Estado de São Paulo
São Paulo, Brazil
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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