Resting Full-cycle Ratio (RFR)-Guided Revascularization

Inclusion Criteria: * Patients with intermediate coronary artery stenosis (visually 50-90% diameter stenosis) who decided to undergoing a RFR-guided coronary intervention according to clinical necessity * Patients who voluntarily decided to participate in this study and signed informed consent Exclusion Criteria: * Severe left ventricular systolic dysfunction (LVEF \<30%) * Cardiogenic shock * Culprit vessel in acute coronary syndrome * Donor vessel to supply chronic total occlusion lesion of non-target vessel * Symptomatic valvular heart disease or cardiomyopathy * Hemodynamic instability at the time of intervention (heart rate \<50 beats per minute, systolic blood pressure \<90mmHg) * Previous CABG with patent grafts to the interrogated vessel * Pregnancy or breastfeeding * Non-cardiac co-morbid conditions are present with life expectancy \<1 year or that may result in protocol non-compliance