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Development of Novel Gastric Cancer Screening and Diagnosis Technologies Using Tongue Imaging and Study of Tongue Image Changes Mechanisms

Recruitingn/aAges 18 Years - 90 YearsAllZhejiang Cancer Hospital
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In plain words

What the trial is, and whether it could suit you

In this study, the investigators will prospectively recruit 100,000 individuals, including gastric cancer patients who have not undergone any anti-tumor treatment and non-gastric cancer participants. The investigators will construct a diagnostic model for malignant tumors based on the combination of tongue imaging, tongue coating, saliva, gastric juice, and fecal multi-omics data (including metagenomics, proteomics, metabolomics, etc.). Additionally, the study will explore the relationship between oral, gastric, and intestinal microbiota and the development of malignant tumors.

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria for Gastric Cancer Patients: * 18≤age≤90 * Histologically or cytologically confirmed gastric cancer * No prior chemotherapy, radiotherapy, biotherapy, immunotherapy or other anti-tumor treatment for gastric cancer * Subject volunteers to join the study, Signs informed consent, has good compliance and can cooperate with follow-up Exclusion Criteria for Gastric Cancer Patients: * Two or more kinds of malignant tumors at the same time * Gastric cancer that has been treated by chemotherapy, radiotherapy, biotherapy, immunotherapy or other anti-tumor therapy * The use of glucocorticoids and antibiotics in the past three months * History of long-term medication * Presence of oral diseases such as tooth and gum diseases * Subjects who had other factors that might force them to terminate the research ahead of time, such as the development of other severe disease (including mental disease) that required combined treatment, seriously abnormal laboratory examination value, and family or social factors that might affect the subject safety or experimental data collection, as judged by the researchers Inclusion Criteria for Healthy Participants: * 18≤age≤90 * Willingness to participate in the study, signing an informed consent form, and demonstrating good compliance Exclusion Criteria for Healthy Participants: * History of malignant tumors * The use of glucocorticoids and antibiotics in the past three months * History of long-term medication * Presence of oral diseases such as tooth and gum diseases * Subjects who had other factors that might force them to terminate the research ahead of time, such as the development of other severe disease (including mental disease) that required combined treatment, seriously abnormal laboratory examination value, and family or social factors that might affect the subject safety or experimental data collection, as judged by the researchers
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What it tests

  • Tongue imaging, tougue coating, saliva, gastric juice, and feces
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Where

1 site
Zhejiang Cancer Hospital
Hangzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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