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Protocol Based Selective Imaging Versus Routine Computed Tomography or Ultrasound in Suspected Appendicitis

RecruitingNAAges 18 Years - anyAllHelsinki University Central Hospital
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to compare protocol based selective imaging to routine imaging in adult patients with suspected appendicitis. The main question\[s\] it aims to answer are: * Does protocol based selective imaging using clinical scoring affect clinical outcome? * Does protocol based selective observation combined with score based selective imaging affect clinical outcome? Participants will be randomized into three groups: * Selective imaging based on Adult Appendicitis Score * Selective observation based on Appendicitis Severity Score combined with selective imaging based on Adult Appendicitis Score * Routine imaging using ultrasound and/or computed tomography Researchers will compare selective imaging groups separately with routine imaging to see if number of negative appendectomies or number of complicated appendicitis is not significantly increased.

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📋 Eligibility rules (as published)
Inclusion Criteria: \- Suspicion of appendicitis Exclusion Criteria: * Time from symptom onset over 72 hours * Age \<18 years * Pregnancy, ruled out by serum or urine HCG measurement in 18- to 49-year-old women * CT-scan or ultrasound already done within the last 3 days (72 hours) * Clinical suspicion of other disease or other reason to perform imaging study * Recruited earlier to the same trial
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What it tests

  • Abdominal imaging
  • Score based selective abdominal imaging
  • Score based selective observation combined with selective abdominal imaging
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Where

3 sites
HUS, Jorvi Hospital
Espoo, Finland
HUS, Meilahti Hospital
Helsinki, Finland
HUS, Hyvinkää Hospital
Hyvinkää, Finland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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