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Evaluation of Topical Rebamipide Versus Topical Betamethasone for Treatment of Oral Aphthous Ulcers

RecruitingPhase 2Ages 18 Years - 70 YearsAllCairo University
NCT06084624 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this randomized clinical trial is to to compare the effect of topical rebamipide to topical betamethasone on pain intensity in patients having recurrent oral aphthous ulcers. The main question it aims to answer is : What is the effect of topical Rebamipide mouthwash compared to topical betamethasone mouthwash on pain reduction in patients with oral aphthous ulcers? Participants will will be divided randomly into the two groups and the following outcomes will be measured: Pain associated with oral ulcers Number of oral ulcers Diameter of oral ulcers Healing time of oral ulcers

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📋 Eligibility rules (as published)
Inclusion criteria: Patients age from 18-70 years old. Patients with active oral ulcers. History of recurrent ulcers in the oral cavity Patients free from any visible oral lesions other than the oral aphthous ulcers. Patient who will agree to participate in the study and take the supplied interventions. E8glusion criteria: * Patients with history of a severe or chronic medical condition including congestive heart failure, malignancy and active infection including tuberculosis, hepatitis and human immunodeficiency virus. * Patients under immunosuppressive drugs. * Patients using topical or systemic treatment agents for the oral ulcers
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What it tests

  • Rebamipide mouthwash
  • Betamethasone mouthwash
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Where

1 site
Faculty of dentistry, Cairo University
Cairo, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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