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Effect and Mechanism of Brain Stimulation for Parkinson's Disease With Cognitive Impairment

Recruitingn/aAges any - 75 YearsAllTianjin Huanhu Hospital
NCT06090682 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study intends to apply structural and functional brain network neuroimaging techniques combined with image post-processing methods to explore the differences in brain network changes in PD patients with cognitive impairment after DBS or TMS.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1\. The clinical diagnosis of PD is consistent with the United Kingdom Parkinson's Disease Society Brain Bank criteria, with disease duration over 5 years, acute levodopa motor response ≥30%, and indication for STN-DBS. Exclusion Criteria: Exclusion criteria included patients with severe cognitive impairment, severe psychiatric disorders, acute levodopa motor response less than 30%, atypical parkinsonism, and contraindications to surgery.
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What it tests

  • Deep Brain Stimulation(DBS) and Transcranial Magnetic Stimulation(TMS)
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Where

1 site
Tianjin Huanhu Hospital
Tianjin, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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