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Efficacy of Songling Xuemaikang Capsules on Grade 1 Hypertension: a Randomized Controlled Trial

RecruitingPhase 4Ages 35 Years - 65 YearsAllXiyuan Hospital of China Academy of Chinese Medic…
NCT06093932 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is: 1. To evaluate the efficacy of Songling Xuemaikang Capsules(SLXMKC) with grade 1 hypertension. 2. To reveal the potiential effects of SLXMKC on vascular function and structure of patients with grade 1 hypertension. 3. To explore the underlying mechanisms of the therapeutic effects of SLXMKC on the intervention of grade 1 hypertension.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age between 35-65 years old, male or female; * Grade 1 essential hypertension; * Taking no antihypertensive drugs or taking antihypertensive drugs irregularly in the past ; * Sign the informed consent; Exclusion Criteria: * Significant liver and kidney dysfunction, ALT and AST upper the twice of normal range, Scr≥2.0mg/dl, eGFR\<60ml/(min·1. 73m2); * Gastrointestinal diseases, which may affect drug absorption; * Be allergic to the clinical trial medicine; * Pregnant or breastfeeding women, men who plan to give birth within half a year; * Combined with other serious primary diseases or malignant tumors; * Hyperlipidemia with or without taking lipid-lowering drugs; * Combined with left ventricular hypertrophy, ABI \< 0.9, CIMT ≥ 0.9mm or atherosclerotic plaque; * Hypertensive comorbidities (cerebrovascular disease, other cardiovascular diseases, renal disease, peripheral artery disease, retinopathy, diabetes); * Other serious conditions in which is not fit for the study.
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What it tests

  • Songling Xuemaikang Capsules
  • Lifestyle intervention
  • Placebo
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Where

5 sites
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Beijing, China
Suzhou Hosptial of Traditional Chinese Medicine
Suzhou, China
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Jinan, China
China Academy of Chinese Medical Sciences Xiyuan Hospital Jining Hospital
Jining, China
China Academy of Chinese Medical Sciences Xiyuan Hospital Shanxi Hospital
Taiyuan, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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