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Improving Overactive Bladder Treatment Access and Adherence

RecruitingNAAges 18 Years - anyFemaleStanford University
NCT06094543 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Overactive bladder (OAB) and urinary incontinence (UI) are chronic debilitating and embarrassing conditions that affect 33 million Americans. Yet, both are underdiagnosed and undertreated with significant financial and health-related consequences. OAB syndrome is characterized by urinary urgency, with and without urinary incontinence, urinary frequency, and nocturia. Evidence-based treatments are available, including behavioral therapy, pharmacotherapy, and minimally invasive procedures. Diagnosis and treatment are also associated with improvement in urinary symptoms and overall quality of life (QOL).3 However, 70-80% of treated patients will discontinue use of therapy in the first year due to one of several factors (e.g., cost, tolerability, inadequate effect). In addition, only 4.7% progress to advanced therapies suggesting undertreatment for those that need it most. Vulnerable populat

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📋 Eligibility rules (as published)
Inclusion Criteria: * Female aged 18 years or older * OAB symptoms for at least 3 months * English/Spanish language skills and cognitive status sufficient to complete all study related materials * Behavioral treatment naïve patients * Previously treated OAB patients without supervised pelvic floor physical therapy or pharmacotherapy within 1 year Exclusion Criteria: * Post void residual urine \> 150ml * Confirmed diagnosis of Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS) * Pregnant or breastfeeding patients * Patients residing in a nursing home * Comorbid neurological conditions, including spinal cord injury, progressive neurologic illnesses (e.g. Multiple Sclerosis, Parkinson's disease) or central nervous system disease (e.g. brain tumor, stroke) * Stage 2 or greater pelvic organ prolapse * Any history of urethral stricture * Any history of pelvic irradiation * Any history of bladder malignancy * Current symptomatic urinary tract infection (UTI), unresolved by the time of enrollment * Hematuria without a clinical evaluation * History or current use of indwelling urinary foley catheterization, suprapubic tube or intermittent catheterization * Patients with UI treated with onabotulinumtoxinA, sacral neuromodulation, or percutaneous tibial nerve stimulation (third line therapies)
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What it tests

  • Patient Engagement Tool
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Where

1 site
Stanford Pelvic Health Center
Redwood City, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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