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Long COVID Brain Fog: Cognitive Rehabilitation Trial

RecruitingNAAges 18 Years - anyAllUniversity of Alabama at Birmingham
NCT06095297 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study will compare two approaches to cognitive rehabilitation in adults with long COVID with persistent, mild to moderate, cognitive impairment. One approach will feature (A) web-based computer "games" that trains how quickly individuals process information that they receive through their senses; (B) in-lab training on everyday activities with important cognitive components, (C) procedures designed to transfer improvements in cognition from the treatment setting to everyday life, and (D) a non-invasive form of vagus nerve stimulation (VNS), i.e., trans-auricular VNS (taVNS). Component B will include work-related tasks. This approach is termed Constraint-Induced Cognitive Therapy (CICT). The other approach will feature (A) web-based computer "games" that train reaction time and eye-hand coordination; (B) in-lab training on relaxation, healthy nutrition, and healthy sleep, (C) procedu

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📋 Eligibility rules (as published)
Inclusion Criteria: * \>3 months post COVID * mild or greater cognitive impairment * moderate or greater brain fog * impairment in performance of daily activities * reside in community * reliable transportation to lab * sufficiently mentally and physically fit * adequate sight and hearing * ability to follow directions, and retain information * sufficient English proficiency Exclusion Criteria: * cognitive impairment due to developmental disability, psychiatric disorder, or substance abuse, TBI or progressive brain disease * stroke prior to the onset of COVID * current substance abuse disorder * prior cognitive processing speed training on DoubleDecision or similar program * cannot tolerate trans-auricular vagus nerve stimulation
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What it tests

  • Processing Speed Training
  • In-lab Instrumental Activities of Daily Living Training
  • In-lab Brain Health Training
  • Transfer Package
  • Follow Up Phone Calls
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Where

1 site
University of Alabama at Birmingham
Birmingham, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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