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Wrist Denervation Vs Exercise in Wrist Osteoarthritis

RecruitingNAAges 18 Years - anyAllKarolinska Institutet
NCT06098586 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

A randomized controlled trial comparing partial wrist denervation to a self-managed exercise therapy program in 140 patients with wrist osteoarthritis.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years. * Chronic wrist pain (≥6 months) due to Scapholunate advanced collapse (SLAC) / Scaphoid non-union advanced collapse (SNAC) grade 1-3 osteoarthritis. * Radiological signs of osteoarthritis on posteroanterior and lateral radiograph. Exclusion Criteria: * Previous PIN or AIN neurectomy. * Rheumatoid arthritis or other chronic inflammatory arthritis. * Symptomatic osteoarthritis in the distal radio-ulnar (DRU), Scapho-trapezio-trapezoid (STT) or thumb carpometacarpal (CMC) joints. * Ongoing infection. * Inability to co-operate with the follow-up protocol. * Systemic or intra-articular glucocorticoids or intraarticular PRP or Hyaluronic acid injections in the affected joint within 3 months prior to enrollment.
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What it tests

  • Self-managed exercise therapy program
  • Partial wrist denervation
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Where

2 sites
Department of hand surgery, Malmo university hospital
Malmö, Sweden
Department of hand handsurgery, Södersjukhuset
Stockholm, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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