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NOL Guided Analgesia During Elective Laparoscopic Surgery Under General Anesthesia

RecruitingNAAges 18 Years - 70 YearsAllAttikon Hospital
NCT06104059 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

The aim of this study is to investigate the hypothesis that the intraoperative use of the nociception level index NOL can reduce opioid consumption in adult patients undergoing elective laparoscopic surgeries under general anesthesia, as well as to explore its effect on post-operative pain and patient recovery.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Adult patients undergoing planned laparoscopic surgery under general anesthesia. Exclusion Criteria: * Emergency surgery. * Pregnancy. * Drug or alcohol abuse in the last 6 months. * Chronic opioid use or patients with chronic pain. * Serious comorbidity \[cardiac disease (atrial fibrillation, ventricular arrhythmias), liver or kidney disease\] * Obesity (BMI \>35). * Permanently implanted pacemaker. * Patients with CNS disease. * Allergy to any of the study drugs. * Patients receiving anticholinergics agonists, ฮฑ2-adrenergic agonists, ฮฒ1-adrenergic antagonists, antiarrhythmic drugs.
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What it tests

  • Nociception level index (NOLโ„ข)
  • Fentanyl
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Where

1 site
2nd Department of Anesthesiology, Attikon University Hospital
Athens, Greece
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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