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Safety and Efficacy of Oral NXC-736 in Adult Participants With Moderate and Severe Alopecia Areata

RecruitingPhase 2Ages 19 Years - 65 YearsAllNEXTGEN Bioscience
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to evaluate the safety and efficacy of NXC-736 monotherapy in participants with severe alopecia areata (AA).

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Men or women between โ‰ฅ19 and โ‰ค65 years of age at the time of informed consent * Moderate and severe alopecia areata as assessed by a SALT score of 25% โ‰ค SALT \< 95% at Screening and Day 1/Baseline * Current episode of hair loss for โ‰ฅ6 months but \<8 years * Stable disease condition (no significant growth of hair) in the last 6 months as assessed by the Investigator * Willing to keep the same hair style and color (eg, hair products, process, and timing for hair appointments) for the duration of the study Exclusion Criteria: * Participants with the following medical history confirmed during screening: * ohter Types of alopecia other than alopecia areata (such as cicatricial/scarring alopecia \[including central centrifugal cicatricial alopecia\], traction alopecia, androgenic alopecia, telogen effluvium, etc.) * Active scalp inflammation, scalp infection, scalp psoriasis, or any other scalp condition that may interfere with the SALT assessment * Previous use of Janus kinase (JAK) inhibitor (oral or topical), including participation in clinical studies of JAK inhibitors
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What it tests

  • NXC736
  • Placebo
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Where

2 sites
Seoul National University Hospital.
Seoul, South Korea
Kyung Hee University Hospital at Gangdong
Seoul, South Korea
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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