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Biological Sex and CTEPH-related RV Dysfunction and Recovery (BIOSPHeRe)

Recruitingn/aAges 18 Years - anyAllIntermountain Health Care, Inc.
NCT06105242 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

1. To identify biological sex differences in baseline RV function in CTEPH 2. To identify biological sex differences in recovery of RV function after PTE surgery in CTEPH 3. To determine if sex hormone levels relate to RV function at CTEPH diagnosis and during recovery after PTE.

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📋 Eligibility rules (as published)
Inclusion criteria * Adult (≥18 years old) patients diagnosed with CTEPH per current guideline standard42 * Subject must have a baseline TTE (within 3 months of diagnosis) with adequate images for RVGLS analysis * Subject must have a right heart catheterization (RHC) at the time of diagnosis * To be included in the Aim 2 analysis, patients must undergo PTE surgery and have a TTE performed 3-9 months after surgery with adequate images for RVGLS strain analysis Exclusion criteria * Unclear or mixed PH diagnosis as designated by an expert clinician at Intermountain PH center * Any subjects \<18 years of age * Patients diagnosed during pregnancy * Patients without a TTE and RHC at time of diagnosis
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What it tests

  • Not listed
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Where

1 site
Intermountain Medical Center
Murray, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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