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The Effect of ACT and Tranexamic Acid on Bleeding in Cardiac Surgery

RecruitingPhase 4Ages 18 Years - anyAllTaichung Veterans General Hospital
NCT06109155 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to the dose effect of tranexamic acid and the level of ACT on bleeding in adult cardiac surgery. The main questions it aims to answer are: 1. Does higher dose of tranexamic acid reduce the amount of bleeding and blood transfusion? 2. Does lower ACT level during cardiac surgery reduce the amount of bleeding and blood transfusion? Participants will divided into four groups which have different tranexamic acid dose and ACT level during cardiac surgery to see if there is any different in the amount of bleeding and blood transfusion.

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📋 Eligibility rules (as published)
Inclusion Criteria: * adult, cardiac surgery with cardiopulmonary bypass Exclusion Criteria: * pregnant * emergency procedure * immune compromised * aortic surgery * end-stage renal disease * liver disease * critical status * incomplete clinical data
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What it tests

  • Tranexamic acid
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Where

2 sites
Taichung Veterans General Hospital
Taichung, Taiwan
Taichung Veterans General hospital
Taichung, Taiwan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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