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Pilot Study of Neurofeedback for Photosensitivity in Mild Traumatic Brain Injury

RecruitingNAAges 18 Years - 65 YearsAllVA Office of Research and Development
NCT06109909 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this study is to complete a pilot study testing the feasibility and acceptability of low-intensity pulse-based transcranial stimulation (LIP-tES) neurofeedback intervention for reducing photosensitivity symptoms in Veterans with a history of mild traumatic brain injury (mTBI). The study will also complete resting-state MRI scans to assess neurophysiological markers of photosensitivity and changes associated with LIP-tES intervention.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Ages 18-65 * Documented history of mTBI at least 6 months prior to initial study visit * Documented symptoms of photosensitivity * Eye exam within the last 12 months documenting best-corrected acuity of 20/20 or better, normal pupillary function, color vision, no abnormalities on OCT scan, and normal Humphrey Visual Field test Exclusion Criteria: * History of strabismus or amblyopia * Significant ocular media opacity that could reduce the amount of light entering the pupil in one or both eyes * Previous or current history of retinal or optic nerve pathology in one or both eyes * History of stroke and/or visual neglect * History of neurodegenerative disease (e.g., Parkinson's, multiple sclerosis) * History of epilepsy or seizures * History of motor tics * Current use of medications or substances that may severely affect pupillary response and/or increase photosensitivity * Individuals with impaired decision-making capacity * Illiterate or no English language proficiency
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What it tests

  • Micro Current Neurofeedback Device using Low-Frequency Pulse-Based Transcranial Electrical Stimulation
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Where

1 site
VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA
Boston, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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