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Cardiac Hemodynamics During Left Ventricular Assist

Recruitingn/aAges 18 Years - anyAllRegion Östergötland
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to exploratively investigate intracardiac geometry and hemodynamics in patients with ongoing HeartMate 3-therapy in the Swedish Southeast Healthcare region. The main question it aims to answer is: \- How do different flow levels in the HeartMate 3 left ventricular assist system influence intracardiac geometry and hemodynamics? Participating research subjects are called upon to undergo three followed photon-counting CT scans, as well as certain echocardiographic imaging, all in one session. The research subject's HeartMate device is connected to software that allows for variations in the pump's flow between these image collections. Analyzed variables includes three-dimensional geometry, CFD-computed parameters such as blood velocity, pressure, turbulence, and blood stasis. The variables are related with device settings and, alongside, selected ech

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📋 Eligibility rules (as published)
Inclusion Criteria: * Connected to Linköping University Hospital ((situated in the Swedish Southeastern healthcare region) * Treatment with HeartMate 3 and implanted for \> 6 months ago * Age \>18 years. Exclusion Criteria: * Reduced kidney function (eGFR below 45 ml/min/1.73m2). * Known iodine contrast allergy * In case of untreated manifest hyperthyroidism * In case of suspected/newly diagnosed thyroid cancer where radioiodine examination/treatment may be relevant * Myasthenia Gravis * Ongoing pregnancy
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What it tests

  • Not listed
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Where

1 site
Linköping University Hospital
Linköping, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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