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GUIDed Growth of the Proximal Femur to Prevent Further Hip MigrAtion in CErebral Palsy Patients

RecruitingNAAges 2 Years - 8 YearsAllErasmus Medical Center
NCT06118736 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In recent literature, the potential of guided growth of the proximal femur to modify hip growth in patients with cerebral palsy has been shown. Using medial hemi-epiphysiodesis of the proximal femur (TMH-PF) morphology of hips at risk of symptomatic (sub)luxation in cerebral palsy (CP) can be changed, aiming to reduce further hip migration and the need for more invasive surgical treatment modalities. Further research is necessary to assess if the results of TMH-PF in combination with adductor tenotomies are significantly better than the results of the current standard of care; adductor tenotomies alone. The investigators objective is to determine whether guided growth of the proximal femur decreases the risk of further hip migration and need for further surgery in cerebral palsy patients.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Spastic CP * GMFCS level IV-V * Aged 2-8 years * At least one hip with an abduction in flexion ≤ 40 degrees * Migration percentage of 30-50% * Head shaft angle \> 145 Exclusion Criteria: * Not fit for surgery * History of bony hip surgery to the affected hip * Severe acetabular dysplasia defined as a gothic arch, an incongruent joint or an acetabular index \> 30 degrees, consistent with A2 and A3 acetabular deformity according to Robin and Graham in an adequately performed radiographs
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What it tests

  • Temporary Medial Hemi-epiphysiodesis of the proximal femur
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Where

5 sites
Amsterdam UMC
Amsterdam, Netherlands
UMC Groningen
Groningen, Netherlands
Maastricht UMC
Maastricht, Netherlands
Sint Maartenskliniek
Nijmegen, Netherlands
Erasmus MC
Rotterdam, Netherlands
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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