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The Swedish BioFINDER - Memory Clinic Study

Recruitingn/aAges any - anyAllSkane University Hospital
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In plain words

What the trial is, and whether it could suit you

The diagnosis of diseases causing memory difficulties or dementia is often challenging. Without the use of advanced methods such as cerebrospinal fluid tests, approximately 25-30% do not receive a correct diagnosis today. However, the investigators have recently developed new blood biomarkers with high diagnostic accuracy, and the investigators now want to investigate whether they can eventually replace cerebrospinal fluid tests. This is because blood tests are much more cost-effective and significantly easier for patients compared to cerebrospinal fluid tests. In this study, 1200 patients undergoing clinical evaluations at the Memory Clinic, Skåne University Hospital in Malmö, are included for blood and cerebrospinal fluid sample collection. The blood samples are sent for analysis using the new blood biomarkers. Subsequently, the results are compared with those from the clinical analys

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: 1. Under investigation for cognitive symptoms at the Memory clinic. 2. Cerebrospinal fluid and blood sampling is planned to be done as part of clinical practice even if the patient is not taking part of this study. Exclusion Criteria: 1. Not undergoing CSF or blood sampling as part of clinical practice. 2. Not undergoing cognitive testing as part of clinical practice.
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What it tests

  • Plasma Amyloid Probability Score 2 (APS 2) score
  • Plasma ptau217/nptau217
  • Plasma ptau217
  • Plasma neurofilament light (NfL)
  • Plasma Ab42/Ab40
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Where

1 site
Skåne University Hospital
Malmö, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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