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Global Burden Estimation of Human Papillomavirus (GLOBE-HPV)

Recruitingn/aAges 9 Years - 50 YearsFemaleInternational Vaccine Institute
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In plain words

What the trial is, and whether it could suit you

This study is a multi-country and multi-site project to estimate the point-prevalence of high-risk (HR) HPV genotype infections among representative samples of girls and women aged 9-50 years, and among specific sub-populations to estimate the incidence of persistent HPV infection among sexually active young women. The data to fulfill the objectives will be collected through a series of Cross-Sectional Surveys (CSS) and Longitudinal Studies (LS) in all 8 countries 3 South Asian countries including Bangladesh, Pakistan, Nepal and 5 sub-Saharan African countries including Sierra Leone, Tanzania, Ghana, Zambia and DR Congo. Qualitative sub-studies (QS) will be conducted in selected countries and populations following the CSS to further understand and unpack risk factors for HPV infection as well as to explore how gender-related dynamics including perceptions of gender norms and stigma, infl

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. 9 to 50 years old (for urban and rural CSSs) at the time of enrollment. 2. Resident in the selected community for at least the past 3 months (with the exception of pastoralists, refugees, and commercial sex workers). 3. Able to understand the purpose of the study and study procedures. 4. If aged 18 years or older or legally considered an emancipated minor, able and willing to provide consent to participate in the study including sample collection. 5. If aged \<18 years (and not considered an emancipated minor), supported in their participation by a parent or guardian who is able and willing to provide consent, and 6. If aged \<18 years (and not considered an emancipated minor), able and willing to provide assent to participate in the study. Exclusion Criteria: 1. Decline consent to participate any activity of the study. 2. A medical condition or other reason, not directly related to HPV infection or HPV-related diseases, in the opinion of the investigator, precludes enrolment in the study.
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What it tests

  • Urine Sample Collection
  • Self-collected Vaginal Swab
  • Blood Samples
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Where

8 sites
Diarrhoeal Disease Research, Bangladesh (icddr,b)
Dhaka, Bangladesh
Institut National pour la Recherche Biomedicale (INRB)
Kinshasa, Democratic Republic of the Congo
University of Health and Allied Sciences (UHAS)
Ho, Ghana
Dhulikhel Hospital Kathmandu University Hospital (DHKUH)
Dhulikhel, Nepal
Aga Khan University (AKU)
Karachi, Pakistan
College of Medicine and Allied Health Sciences (COMAHS)
Freetown, Sierra Leone
Mwanza Intervention Trial Unit (MITU)
Mwanza, Tanzania
ZAMBART
Lusaka, Zambia
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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