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Course for Brain Fatigue After Graves' Disease Controlled Study

RecruitingNAAges 18 Years - 72 YearsAllVastra Gotaland Region
NCT06134219 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

BACKGROUND. Mental fatigue (MF) is common in the most common form of hyperthyroidism, Graves' disease (GD). Clinically, MF is the primary mental symptom in patients with GD and is characterized by difficulties maintaining attention, exhaustion during cognitively demanding tasks, memory difficulties, irritability, and emotional lability. It may be the main contributing factor to the continued low quality of life in many patients with GD. MF can be measured with an MF score (MFS). The pathophysiology is unknown. There is no medical treatment, which requires patients to adapt to the situation. AIM. In this project, the investigators want to test the hypothesis that mental fatigue improves - with secondary benefits on mental capacity, quality of life (QoL), and function - in patients with persistent mental fatigue in GD, through an MF course as an addition to standard care, compared to pati

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📋 Eligibility rules (as published)
Inclusion Criteria: * 18-72 years old * 15-72 months since first Graves' diagnosis * high free thyroxin and thyroid antibodies (TRAb) at diagnosis * euthyroid the last 6 months normal thyroid hormone levels at inclusion * symptoms on MF in connection to Graves diagnosis * MF-scale ≥10.5 points Exclusion criteria: * other diseases or situations that may be associated with mental fatigue (such as other active inflammatory disease, neurological disease) * pregnancy * lactation * assessment that the patient cannot follow the study protocol.
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What it tests

  • MF course
  • Usual health care
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Where

1 site
Agneta Lindo
Gothenburg, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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