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Does Sexual Intercourse Affect the Outcomes of Frozen-thawed Embryo Transfer?

RecruitingNAAges 18 Years - 41 YearsFemaleSheba Medical Center
NCT06134609 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to test whether sexual intercourse the night after embryo transfer affects thawed embryo implantation rates. Women undergoing one of their first four frozen embryo transfers with a good quality embryo will be randomly assigned to two groups. The study group is subjected to have intercourse without using a condom at the evening/night after the embryo transfer, while the control group will abstain from intercourse for the next 48 hours after the transfer. Researchers will compare the ongoing pregnancy rates between the intervention group and the control group.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Women age 18-41yrs. 2. BMI (body mass index) of 18-35 kg/m². 3. Patients undergoing one of their first four frozen embryo transfers. 4. Patients transferring a good quality embryo, either a cleavage stage embryo or a day 5 blastocyst. Exclusion Criteria: 1. Patients age above 42. 2. Moderate or poor-quality embryos. 3. Patients with hydrosalpinx or uterus malformations. 4. Patients who are not able or are not interested in having vaginal intercourse (same sex couples for example). 5. Couples undergoing preimplantation genetic diagnosis when natural cycle frozen embryo transfer is planned (as they are instructed to avoid intercourse).
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What it tests

  • Sexual intercourse
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Where

1 site
Sheba Medical Center
Ramat Gan, Israel
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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