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The Correlation Between Microbiome of Esophageal Cancer Patients and Post Esophagectomy Anastomotic Leaks

Recruitingn/aAges 18 Years - 85 YearsAllRambam Health Care Campus
NCT06136845 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Esophageal cancer continues to be one of the most challenging topics and the subjects of numerous studies. Surgery is the mainstay for curative treatment and the need to improve all aspects of perioperative management in order to reduce morbidity and mortality, continues to be of immense importance. Cited as the sixth most common cause of cancer-related death worldwide, esophageal cancer has a distinct geographic distribution known as the esophageal cancer belt: north central China through the central Asian republics to northern Iran, and from eastern to southern Africa. Squamous-cell carcinoma and adenocarcinoma are the two main histological subtypes of esophageal cancer, in a geographic differentiation as well, with squamous-cell carcinoma as the most common esophageal cancer subtype worldwide. Though adenocarcinoma is at a considerable rise in Western populations and has become the

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📋 Eligibility rules (as published)
Inclusion Criteria: * Cancer patients who have a surgery sample at Rambam Pathology Department * Given written informed consent to Rambam BioBank or Midgam for collection, storage, collection of information and use for future research * Patients with non-metastatic esophageal cancer (mid/Siewert 1/Siewert 2) who developed esophageal leak * Patients with non-metastatic esophageal cancer (mid/Siewert 1/Siewert 2) who had no post-op complication. Exclusion Criteria: • Patients who had complete response are excluded due to lack of tumoral tissue in the specimen for analysis
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What it tests

  • Not listed
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Where

1 site
Rambam Health Care Campus
Haifa, Israel
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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