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โ† Trials
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Safety and Efficacy of RRG001 Gene Therapy in Subjects With Neovascular Age-related Macular Degeneration (nAMD)

RecruitingPhase 1, Phase 2Ages 50 Years - anyAllShanghai Refreshgene Technology Co., Ltd.
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In plain words

What the trial is, and whether it could suit you

A Phase I/IIa, Dose-escalation and Dose-expansion Study to Evaluate the Safety and Efficacy of Single Subretinal Injection of RRG001 in Subjects With Neovascular Age-related Macular Degeneration

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Subjects that are willing and able to follow study procedures. * Patinets โ‰ฅ50 years old. * Clinically diagnosed with CNV secondary to nAMD. * BCVA of the study eye is โ‰ฅ5 letters and โ‰ค73 letters(Snellen 20/800\~20/40), as well as that of the other eye โ‰ฅ19 letters(Snellen 20/400). * Responding to anti-VEGF Exclusion Criteria: * Presence of any other eye diseases other than nAMD in study eye that would affect the treatment or confusing the interpretation of the study results , as judged by the investigator. * CNV or macular edema in the study eye secondary to any causes other than AMD. * Uncontrolled glaucoma. * Uncontrolled hypertension despite medication. * Pregnant or lactating women or individuals with reproductive potential who are unwilling to take effective contraception during the study period.
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What it tests

  • RRG001
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Where

1 site
Tianjin Medical University Eye Hospital
Tianjin, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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