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Efficacy of Vildagliptin Versus Metformin in Poly Cystic Ovary Syndrome

RecruitingPhase 2, Phase 3Ages 18 Years - 50 YearsFemaleOctober 6 University
NCT06142656 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects approximately 10-20% of women of reproductive age, Management strategies for PCOS include lifestyle modifications such as diet and physical activity that are the first-line approach to treatment; however, they are reported to be minimally effective in reducing weight or treating PCOS-related symptoms.Pharmacological options are also available; however, they are not explicitly approved for PCOS treatment as they have been primarily used to treat other conditions such as T2DM

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📋 Eligibility rules (as published)
Inclusion Criteria: -Women diagnosed with PCOS according to Rotterdam 2003 criteria National Institute of Health criteria. Exclusion Criteria: * Patients with history of diabetes mellitus (Type 1 or 2). * Patients with liver or renal dysfunction; inflammatory diseases; autoimmune disease; cancer, acute cardiovascular event within last three months * Known hypersensitivity or contraindications to use dipeptidyl peptidase-4 (DPP-4) inhibitors * Eating disorders (anorexia, bulimia) or gastrointestinal disorders
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What it tests

  • Metformin Hydrochloride tablet
  • Vildagliptin 50 MG
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Where

1 site
October 6 university hospital
Giza, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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