🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Nafamostat Efficacy in Phase 3 Registrational CRRT Study

RecruitingNAAges 18 Years - 80 YearsAllTalphera, Inc
NCT06150742 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

A prospective, randomized, placebo-controlled clinical study to investigate the safety and efficacy of Niyad (nafamostat mesylate) for anticoagulation of extracorporeal blood circulating through a dialysis filter in patients undergoing CRRT who cannot tolerate heparin or are at higher risk for bleeding.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Patients requiring CRRT or undergoing CRRT initiated within the prior 48 hours * Patients who cannot tolerate heparin or are at high risk of bleeding Exclusion Criteria: * Patients weighing less than 50 kg * Patients receiving systemic anticoagulation * Patients with active bleeding
💊

What it tests

  • Niyad (nafamostat mesylate)
  • Placebo (0.9% NaCl)
📍

Where

10 sites
University of California Los Angeles
Los Angeles, United States
AdventHealth
Orlando, United States
Henry Ford Health
Detroit, United States
University of New Mexico
Albuquerque, United States
Northwell Health
Great Neck, United States
Mount Sinai
New York, United States
Cincinnati Children's Hospital Medical Center
Cincinnati, United States
University of Pittsburgh Medical Center
Pittsburgh, United States

…and 2 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy