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The Role of Histamine in Muscle Protein Synthesis Following Resistance Training

RecruitingNAAges 18 Years - 45 YearsMaleUniversity Ghent
NCT06152497 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Blocking histamine H1/H2 receptors blunts chronic endurance training adaptations. The current study addresses the following research question: "What is the influence of histamine H1 signaling on training adaptations following ten weeks of resistance training in human skeletal muscle." Results from this study will yield more insights into the molecular mechanisms of adaptations to exercise training.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Male * 18-45 years * Not to medium physically active Exclusion Criteria: * Smoking * Chronic disease * High blood pressure * Supplement or medication intake * Seasonal allergies * Vegetarian / vegan * Resistance trained
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What it tests

  • Placebo
  • H1 blockade: Telfast: 180mg Fexofenadine
  • Resistance training
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Where

1 site
Department of movement and sports sciences, Ghent University, Belgium
Ghent, Belgium
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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