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INtensity of OVarian Stimualtion and Euploid Embryos

RecruitingPhase 4Ages 38 Years - 42 YearsFemaleFundación Santiago Dexeus Font
NCT06154083 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This randomized trial was designed as a no-inferiority trial aiming to evaluate if the intensity of stimulation (a milder vs a more intense approach) may have an impact on the number of euploid embryos and the morpho kinetic parameters in advanced age women undergoing PGT-A with a PPOS protocol.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Infertile patients with indication for IVF * Undergoing preimplantation genetic screening cycles * AMH \>= 1.5 ng/ml and \< 3.5 ng/ml (AMH result of up to one year will be valid) * BMI 18.5 - 30 Kg/m2 Exclusion Criteria: * Severe male factor requiring TESE (testicular sperm extraction) * AMH \< 1.5 ng/ml or \>= 3.5 ng/ml * Administration of any other drug potentially interfering with the treatment * Contraindication for hormonal treatment * Recent history of severe disease requiring regular treatment (clinically significant concurrent medical condition that could compromise subject safety or interfered with the trial assessment). * Monogenic disease to be detected with PGT-M
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What it tests

  • Follitropin-delta (Rekovelle) 20 mcg/day from D1
  • Follitropin-delta (Rekovelle) 15 mcg/day from D1
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Where

1 site
Hospital Universitario Quiron Dexeus
Barcelona, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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