Powered Prosthesis for Use With TF Osseointegration Recipients

Inclusion Criteria: * Unilateral lower limb amputation at the transfemoral level * Existing prosthesis wearer * K2/K3/K4 level ambulation * 18-70 years old * Mini-Mental State Exam (MMSE) score greater than 17 * Ability to demonstrate proper safety with passive prosthesis * Candidate for a myoelectric prosthesis (can generate mV level electromyographic EMG signals as detected by surface electrodes * Candidate for OI surgery as verified by surgical team or has previously received OI * Candidate for TMR surgery as verified by surgical team or has previously received TMR Exclusion Criteria: * Unable to successfully receive osseointegration and TMR * Significant new injury that would prevent use of a prosthesis: Ability to consistently wear prosthesis and perform activities of daily living and specific performance tasks is necessary to properly evaluate the relative benefits of the intervention * Cognitive impairment sufficient to adversely affect understanding of or compliance with study requirements, ability to communicate experiences, or ability to give informed consent: The ability to understand and comply with requirements of the study is essential in order for the study to generate useable, reliable data. * Visually impaired * Proximal nerve injury that prevents TMR * Individuals who smoke: may interfere with OI process from both bone healing and soft tissue standpoints * Individuals with active implants. * Significant comorbidity that would preclude completion of the study, use of prostheses, or would otherwise prevent data acquisition by researchers