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โ† Trials
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Middle Meningeal Artery Embolization for Chronic Subdural Hematomas (STORMM)

RecruitingNAAges 18 Years - 100 YearsAllUniversity Hospital, Geneva
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In plain words

What the trial is, and whether it could suit you

Chronic Subdural Hematomas (cSHD) are common, and due to cerebral compression, often result in neurological impairment and reduced consciousness. Surgery is typically performed once neurological symptoms develop. Recent studies suggest that arteries nourished by the middle meningeal artery (MMA) may be responsible for hematoma progression and that MMA embolization is clinically useful. There is less evidence, that embolization of MMA also may be a treatment option for individuals without surgical treatment. The investigators propose a multicentre study to investigate both potentials: (1) Assessment of efficacy of embolization after surgery to reduce recurrence and improve outcomes by conducting a randomized trial (randomization arms; Arms 1 and 2), (2) Assessment of embolization-alone efficacy when surgery is contraindicated or refused (embolization-only arm, Arms 3 and 4).

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age: 18-100 * Consent possible * cSDH located at the convexities * Patients with symptomatic cSDH * Patients with asymptomatic large chronic/subacute hematoma after 6 weeks of failed conservative treatment Exclusion Criteria: * Consent not possible * Pregnancy * Prisoner * Angiography contraindication * Patient for whom follow-up is problematic (e.g. distant residency, homeless โ€ฆ) * Previous surgery for cSDH
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What it tests

  • MMA embolization
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Where

2 sites
Geneva University Hospitals
Geneva, Switzerland
EOC
Lugano, Switzerland
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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