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Perioperative Dexmedetomidine on Postoperative Delirium in Patients With Brain Tumors

RecruitingNAAges 18 Years - anyAllBeijing Tiantan Hospital
NCT06164314 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Neurosurgery is a risk factor for delirium. Dexmedetomidine might reduce delirium by reducing neuroinflammation, improving postoperative analgesia and sleep quality. The the primary hypothesis is that perioperative administration of dexmedetomidine can reduce the incidence of postoperative delirium

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with temporal glioma scheduled for a elective craniotomy * Age ≥18 years * Obtain written informed consent. Exclusion Criteria: * Patients with severe preoperative cognitive impairment * History of traumatic brain injury or previous neurosurgery * History of psychotropic medications * Allergy to dexmedetomidine * Pregnant or lactating women * History of obstructive sleep apnoea syndrome * Severe bradycardia(heart rate \<40 beats/min), sick sinus syndrome or second-to-third degree atrioventricular block * Severe hepatic dysfunction * Severe renal dysfunction
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What it tests

  • Dexmedetomidine
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Where

1 site
Beijing Tiantan Hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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