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Capture of Healthy Gut Bacteria Associated to High Fiber Diet

Recruitingn/aAges 20 Years - 50 YearsAllInstitut National de Recherche pour l'Agriculture…
NCT06166810 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The role of the intestinal microbiota on health is now well recognised, and diet is one of the factors influencing the maintenance of a healthy intestinal microbiota. More specifically, the consumption of fruit, vegetables and cereals is associated with good health and, in particular, with an increase in the relative abundance of bacterial groups described as beneficial. To date, a large number of bacterial species in the intestinal microbiota have yet to be isolated and cultivated, which limits the characterisation of their potential health benefits. In order to isolate and cultivate these intestinal bacteria, it is particularly relevant to recruit individuals with a high-fibre diet.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Healthy adult subjects ; * Age between 20 and 50 (limits included) ; * BMI between 18.5 and 25 kg/m2 (excluding limits) ; * Consumption of more than 5 portions of fruit and vegetables a day; * Intake of at least 25g of dietary fibre per day; * A varied diet with little processed food. Exclusion Criteria: * Antibiotics and/or transit modulators taken in the 3 months prior to sampling; * Known pathologies; * Current treatment; * History of digestive surgery having an impact on the microbiota, deemed incompatible with the study (bariatric surgery); * Consumption of food supplements based on protein preparations, probiotics or prebiotics; * Smoking (even occasionally); * Alcohol consumption \> 2 glasses (i.e. 20 g) per day; * Intense sporting activity; * Pregnant or breast-feeding women; * Persons under legal protection (curatorship, guardianship, etc.); * Volunteers taking part in another intervention study; * Persons refusing to be registered on the French Ministry of Health's Fichier National des Volontaires Sains (National Register of Healthy Volunteers); * Subject not affiliated to the social security system; * Subject in a period of exclusion from a previous study or having received a total amount of compensation exceeding 6000 euros over the 12 consecutive months prior to the start of the trial (after verification in the Fichier des Volontaires pour la Recherche Biomédicale).
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What it tests

  • Not listed
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Where

1 site
CRNH Auvergne
Clermont-Ferrand, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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