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Effect of Individualized PEEP on Postoperative Pulmonary Complication in Bariatrics

RecruitingNAAges 16 Years - anyAllAin Shams University
NCT06168162 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Ventilation with low tidal volume and high PEEP (positive end expiratory pressure) has been shown to improve oxygenation in patients with ARDS (acute respiratory distress syndrome). In obese patients undergoing laparoscopic bariatric surgeries, the risk of postoperative pulmonary complications (PPCs) increases significantly with general anesthesia. Previous studies have shown that protective lung ventilation strategies could improve intraoperative oxygenation and lung mechanics. In this study would compare the effect of optimum individualized high PEEP versus standard PEEP - on postoperative pulmonary complications

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients were eligible for participation if the met the following criteria * Age between 18 and 60 years old. * Body mass index \> 40 * Laparoscopic bariatric elective surgery under general anesthesia. * ARISCAT (Assess Respiratory Risk in Surgical Patients in Catalonia) score ≥ 45 . ARISCAT score is a clinically practical seven-factor scoring system to assess the risk of a composite PPC. Exclusion Criteria: * Previous lung surgery * ASA status III or IV. * Moderate to severe obstructive or restrictive lung disease . * Persistant intraoperative hemodynamic instability . * Need for postoperative mechanical ventilation
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What it tests

  • titated PEEP to best static compliance
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Where

1 site
Ain shams university
Cairo, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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