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Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients

RecruitingEARLY Phase 1Ages 18 Years - 75 YearsAllNational Institute of Cardiology, Laranjeiras, Br…
NCT06169241 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Arterial hypertension (AH) has been identified as an important public health problem and considered a new epidemic with high mortality and morbidity. High blood pressure (BP) levels increase the chances of coronary artery disease (CAD), heart failure (HF), stroke, chronic renal failure (CRF) and death. Beetroot powder may be an easier way to increase the availability of nitric oxide and consequently vasodilation in these patients. However, studies are needed to evaluate its benefits in patients with AH.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Resistant hypertension, with a diagnosis described in the medical record, without changing medications or increasing doses in the last 30 days. Exclusion Criteria: * neoplasms * heart failure * use of medications with nitrate in their formula * patients undergoing renal denervation
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What it tests

  • Beetroot extract
  • Placebo
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Where

1 site
National Institute of Cardiology
Rio de Janeiro, Brazil
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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