AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Radiofrequency Ablation vs Doppler-guided Haemorrhoidal Artery Ligation in the Treatment of Haemorrhoidal Disease

RecruitingNAAges 18 Years - 80 YearsAllCentre Hospitalier Departemental Vendee
💬

In plain words

What the trial is, and whether it could suit you

Surgical treatment of grade II/III internal haemorrhoidal disease is indicated in the case of medical and/or instrumental treatment failure. Minimal invasive alternatives to haemorrhoidectomy have been introduced in the last decades to treat grade II/III haemorrhoids. Doppler-Guided haemorrhoidal artery ligation (DGHAL) represents a good therapeutic option in this condition with good short and mid-term outcomes but postoperative recurrence rates up to 35% at 5 years. Recently, a technique of radiofrequency ablation (RFA) has been introduced with promising outcomes. A recent systematic review reported a significant improvement of preoperative symptoms and a recurrence rate \< 5%. To date, there is no study comparing DGHAL to RFA in the treatment of grade II/III haemorrhoids. The aim of this study is to demonstrate the non-inferiority in terms of failure rate of haemorrhoidal radiofrequ

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Major patient, * With symptomatic Grade II or III haemorrhoidal disease, * Requiring surgical management, * Patient able to understand the protocol and having given written informed consent to participate in the study, * Patient affiliated to the social security system or entitled to it. Exclusion Criteria: * Hemostasis disorders * Active external haemorrhoidal disease (thrombosis) * History of surgical procedure for treatment of haemorrhoids (instrumental treatment is not a contra-indication) * Associated proctological pathology (anal fissure, chronic suppuration, external rectal prolapse) * History of colorectal cancer * History of inflammatory bowel disease * History of rectal resection * Patient participating in another interventional clinical research protocol involving a drug or clinical investigation of a medical device * Patient who is pregnant, breastfeeding or able to procreate without effective contraception\* at the time of inclusion * Patient under guardianship, curators or deprived of liberty. * Patient under court protection. * oral contraceptive (pill), monthly vaginal ring, weekly transdermal patch, subcutaneous implant, intrauterine devices (IUD), or sterilisation.
💊

What it tests

  • Doppler-Guided Haemorrhoidal Artery Ligation
  • Radiofrequency ablation
📍

Where

18 sites
Centre Hospitalier Universitaire
Amiens, France
Centre Hospitalier Universitaire
Angers, France
Maison de Santé Bagatelle
Bordeaux, France
Centre Hospitalier Privé
Brest, France
Clinique du val d'Ouest
Écully, France
Centre Hospitalier Départemental de Vendée
La Roche-sur-Yon, France
Hôpital de la Louvière
Lille, France
CHU Limoges
Limoges, France

…and 10 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy