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Effects of Cetoleic Acid on Atherosclerosis (Ketolinsyre's Effekt på Aterosklerose)

RecruitingNAAges 20 Years - 70 YearsAllOslo University Hospital
NCT06172335 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In this Randomized Controlled Trial (RCT) we want to study the effect of an oil with high concentrations of cetoelic acid (C22:n1-11) (intervention) compared to supplements with a low concentration of cetoleic acid (control), but with equivalent content of EPA og DHA, on plasma levels of epa and dha as well as atherosclerotic markers, glucose, c-peptide and triglycerides in a patient group with a metabolically unfavorable phenotype. Our primary endpoints are changes in the concentration of EPA and DHA in plasma.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Triglycerides \> 1.7 mmol/L * Waist measurement \> 80 cm (women) and \> 94 cm (men) Exclusion Criteria: * Chronic disease (liver/kidney/metabolism) * Ongoing active cancer treatment * Excessive alcohol consumption (\>40g/day) * Pregnant/breastfeeding or planned pregnancy during the intervention * High intake of fish (\>3 weekly meals) * Level of free thyroxine (T4) and triiodothyronine (T3) outside reference ranges. * Hypertension (≥ 160/ 100 mmHg) * Total cholesterol \> 7.8 mmol/L * Blood donation during the intervention period * Difficulty following the protocol * Smoking or sniffing * Regular use (\> 1 day/week) of anti-inflammatory drugs * Regular use of omega-3 supplements/cod liver oil * Drug use other than stable use of statins, hypertension drugs (Ca antagonists, diuretics and beta blockers). * Hormonal treatment excluding stable use of thyroxine and birth control pills/contraceptive rod
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What it tests

  • Cetoleic acid
  • Control oil
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Where

1 site
Oslo University Hospital
Oslo, Norway
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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