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โ† Trials
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DCE-MRI Guided Neoadjuvant Chemotherapy for Borderline Resectable Pancreatic Cancer

RecruitingNAAges 19 Years - anyAllOhio State University
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In plain words

What the trial is, and whether it could suit you

The goal of this study is to test whether chemotherapy guided by a new imaging method named DCE-MRI can more effectively reduce a pancreatic tumor, enabling curable surgery, over the conventional method when a tumor is categorized as borderline resectable pancreatic cancer. UAB radiological research team has been studying a cutting-edge imaging technique named dynamic contrast-enhanced magnetic resonance imaging, or DCE-MRI, for over 10 years. This technique has been globally used to calculate the blood flow of various tissues, including tumors. Blood flow often serves as a critical indicator showing a disease status. For example, a pancreatic tumor typically has low blood flow, so it can be used as an indicator to identify the presence of a pancreatic tumor. In addition, an effective therapy can result in the increase of blood flow in a pancreatic tumor during the early period of treatm

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Adult patients (age 19 years or older). * Patients with newly diagnosed and untreated borderline resectable pancreatic cancer. * Patients with signed informed consent. Exclusion Criteria: * Any history of prior radiation or chemotherapy or surgical removal for pancreatic cancer. * Participants with safety contraindications to MRI examination (determined by standard clinical screening). * Participants who are pregnant, lactating or are planning to become pregnant during the study. * Participants who are planning to father a child during the study.
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What it tests

  • Point-of-care Portable Perfusion Phantom (P4)
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Where

2 sites
Indiana University Medical Center
Indianapolis, United States
The Ohio State University
Columbus, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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