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Visceral Adiposity, Vagal Tone and Food Preferences: a Pilot Study

Recruitingn/aAges 18 Years - 45 YearsAllLaval University
NCT06175988 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Food preferences are defined by a number of measurable parameters, such as per se food choices, sensitivity of taste and olfactory sensory perceptions, hedonic appreciation of foods ("liking") and motivation to consume them ("wanting"). These food preferences are fundamental to the quality of food intake, and are therefore a key factor influencing weight loss or maintenance of a stable weight. Obesity is also associated with reduced sensory sensitivity to taste and smell, as well as disturbances in the responses of the food reward system. However, the internal, or physiological, mechanisms impacting these food preferences are still poorly understood. To date, several studies seem to point to the role of body composition, in particular visceral adiposity, or adiposity surrounding the digestive organs. Indeed, a high level of visceral adiposity is associated with the onset of numerous car

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📋 Eligibility rules (as published)
Inclusion Criteria: * Have a BMI between 18.5 and 35 kg/m²; * French-speaking; * Be able to travel to the Research Center of the Institut Universitaire de Cardiologie et Pneumologie de Québec for an investigative visit. Exclusion Criteria: * Smokers ; * Women who know they are pregnant, breastfeeding or menopausal; * Who have been diagnosed with type I or type II diabetes; * Having undergone bariatric surgery or obesity medication (GLP1 analogue, naltrexon-bupropion combination, etc.); * Presenting an allergy or intolerance to one of the products used in the sensory tests (taste test: sucrose, sodium chloride, citric acid, quinine hydrochloride dihydrate; olfactory test: citrus, lemongrass, cinnamon, mint, peppermint, banana, anise, turpentine, garlic, coffee, apple, clove, pineapple, rose, geranium, eucalyptus, wormwood, fennel, caraway, leather, n-butanol, linalool, pyridine, diethyl phthalate, propylene glycol); * Have a history of pathologies which, in the investigator's opinion, could interfere with the study criteria, such as ENT, neurological, upper digestive or cardiac pathologies; * Receiving long-term pharmacological treatment, in particular antidepressants, antipsychotics, benzodiazepines, beta-blockers, etc. ; * Presenting or having presented in the last 6 months a thymic episode such as depression, bipolar disorder, etc. ; * Wearing a cardiostimulator (pacemaker); * Minors or adults under guardianship.
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What it tests

  • Visceral adiposity
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Where

1 site
IUCPQ
Québec, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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