AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Effects of Nattokinase on Inflammation and Cardiovascular Risk Markers in Patients With Dyslipidemia

RecruitingNAAges 18 Years - anyAllUniversidade Federal Fluminense
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

The study aims to evaluate the effect of the nattokinase enzyme on inflammation and markers of cardiovascular risk in participants with dyslipidemia. A longitudinal double-blind randomized clinical trial will be carried out, involving hypertensive participants with dyslipidemia for two months.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Both sexes; * Over 18 years of age; * Isolated increase in LDL-c (LDL-c โ‰ฅ 160 mg/dL); * Isolated increase in triglycerides (TG โ‰ฅ 150 mg/dL or โ‰ฅ 175 mg/dL, without fasting); * increased LDL-c (LDL-c โ‰ฅ 160 mg/dL) * TG (TG โ‰ฅ 150 mg/dL or โ‰ฅ 175 mg/dL, without fasting); * Reduction in HDL-c (men \< 40 mg/dL and women \< 50 mg/dL) alone or in association with an increase in LDL-c or TG. If TG โ‰ฅ 400 mg/dL. * Individuals who are already using lipid-lowering therapy (statins or non-statins) will also be included. Exclusion Criteria: * Participants with autoimmune and infectious diseases, diabetes, cancer and AIDS; * Pregnant women; * Participants using catabolic drugs or antibiotics * Participants on anticoagulant medication * Participants using antioxidant vitamin supplements, prebiotic, probiotic or synbiotic and who are allergic to corn or soy starch.
๐Ÿ’Š

What it tests

  • Nattokinase
  • Placebo
๐Ÿ“

Where

1 site
Denise Mafra
Rio de Janeiro, Brazil
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy