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โ† Trials
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Analysis of the Prevalence of Sensitization to Plants Containing Gibberellins Using Realistic Skin Prick Tests

RecruitingNAAges 5 Years - anyAllUniversity Hospital, Montpellier
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In plain words

What the trial is, and whether it could suit you

Gibberellin-related proteins (GRPs) are proteins contained in both pollens and vegetables and are associated with an increased risk of severe food allergy reactions. The best characterized one the only one for which a specific IgE (Immunoglobulin E) may be dosed in current clinical practice is Pru p 7, an allergen contained in peaches (Prunus persica). Sensitization to GRPs seems to be greater in areas with high exposure to pollens of the Cupressaceae family (as in the Montpellier region in Southern France); a subtype of Cupressaceae pollinosis, characterized by sensitization to Pru p 7 has been shown to be responsible for severe peach allergies. To date, there has been no real analysis of the prevalence of sensitization to GRPs, or of possible cross-sensitization between plants and foods containing GRPs. Main food containing GRPs with a high level of homology with Pru p 7 include apple

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Patients aged at least 5 years * Patients consulting at the Allergy Unit of the University Hospital of Montpellier for any type of allergy work-up/evaluation * Oral consent from the patient and, where applicable, from at least one of the patient's legal representatives in the case of minors. Exclusion Criteria: * Patients treated with antihistamines or psychotropic drugs with antihistaminic action during the 7 days prior to inclusion * Patients with pathologies that prevent the performance of prick tests (e.g. severe peripheral neuropathy, cutaneous anergy). * Patients with dermographism. * Patient taking part in another study which may influence the results of the prick tests. * Patients in an exclusion period determined by a previous study. * Pregnant, parturient or breast-feeding women. * Patients or their legal representatives under court protection, guardianship or trusteeship. * Patients or their legal representatives who are not members or beneficiaries of a health insurance scheme. * Patient or his/her legal representative unable to read and understand French fluently.
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What it tests

  • Skin prick test
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Where

1 site
University Hospital of Montpellier
Montpellier, France
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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