🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

The Effects of Various Concentrations of Ropivacaine on the Onset and Duration of Ankle Blocks

RecruitingNAAges 18 Years - 75 YearsAllZiekenhuis Oost-Limburg
NCT06185608 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Peripheral nerve blocks are essential in ensuring effective regional anesthesia and postoperative analgesia in forefoot surgery for hallux valgus repair, with or without minor concomitant toe procedures. Many factors influence the onset and duration of peripheral nerve blocks. In the advent of ultrasound-guided nerve blocks, the accuracy in administering LA has significantly improved, potentially reducing the required dosage, which is also associated with less risk for toxicity. However, the effect of the concentration of LA on the onset time and duration of ultrasound-guided ankle blocks for forefoot surgery has not yet been studied. This poses a clinically relevant dilemma regarding the necessity of administering lower or higher concentrations of ropivacaine to achieve a clinically relevant faster onset time and longer duration of an ankle block.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Provide signed and dated informed consent * Age 18 up to and including 75 years, scheduled for elective forefoot surgery for hallux valgus repair, with or without one or more of the following: minor toe procedures, osteotomies, arthrodesis or toe extensor/flexor procedures, under unilateral ankle block at ZOL Genk * ASA physical I-II-III * Able to ambulate (ability to walk independently, with or without assistive devices) * Able to learn and perform study sensory and motor assessment by exhibiting sensitivity to pinprick, cold, and light touch (tested beforehand with pinprick/cold/ light touch sensation test) as the patient will have to perform these sensory and motor assessments by him/herself at home at postoperative day 0 to 2 Exclusion Criteria: * Language barrier * Preexisting lower extremity neuropathy * Contraindications to ankle block (local infection, edema, burn, soft tissue trauma, or distorted anatomy with scarring in the area of block placement) * Contraindications for use of NSAIDs * Allergy to local anesthetics * Uncontrolled anxiety, psychiatric or neurological disorder that might interfere with study assessment * Weight below 50 kg based on a maximum dose of 3 mg/kg ropivacaine and a maximum dose of 150 mg ropivacaine. * Preoperative use of opioids or gabapentin less than 3 days before surgery * Contraindications for use of paracetamol * Contraindications for use of tramadol
💊

What it tests

  • 0.25% ropivacaine
  • 0.5% ropivacaine
  • 1% ropivacaine
📍

Where

1 site
Ziekenhuis Oost-Limburg
Genk, Belgium
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy