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Exhaled Breath Condensate Analysis in Mechanically Ventilated Patients

Recruitingn/aAges 18 Years - anyAllThe Institute of Molecular and Translational Medi…
NCT06189924 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Mechanically ventilated intensive care patients will be sampled for a small amount of exhaled breath condensate from the ventilator circuit and for venous blood. Proteomic analysis of the exhaled breath condensate will be performed using mass spectrometry and in the blood sample, corresponding changes in the DNA, RNA, proteins, and metabolites will be studied. Resulting profiles will be correlated with routinely monitored parameters in order to identify patterns corresponding to various pathologies in order to enable their early detection.

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📋 Eligibility rules (as published)
Inclusion Criteria: Intensive care setting Mechanical ventilation Ventilator/ventilator circuit technically suitable for sampling of exhaled breath condensate Exclusion Criteria: Mechanical ventilation challenging to the extent that the insertion of the sampling kit into the ventilator circuit would substantially increase the risk for respiratory deterioration
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What it tests

  • Proteomic analysis of exhaled breath condensate
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Where

2 sites
Institute of Molecular and Translational Medicine, Palacky University
Olomouc, Czechia
University Hospital Olomouc
Olomouc, Czechia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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