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Atrophic Gastritis Predicts the Risk of Gastric Cancer

Recruitingn/aAges 18 Years - 70 YearsAllShanghai Jiao Tong University School of Medicine
NCT06203327 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Despite declining incidence rates, gastric cancer (GC) ranks the fourth leading cause of cancer-related mortality and the fifth most common cancer worldwide, with the highest incidence reported in Eastern Asia. The 5-year overall survival rate of early GC exceeds 90%, which was well above advanced GC. Most intestinal-type GCs follow the Correa cascade-inflammation,atrophy, intestinal metaplasia (IM), dysplasia and subsequent carcinoma. The presence of gastric mucosal atrophy and intestinal metaplasia are important risk factors for GC. The purpose of this study was to investigate the incidence of GC attributed to atrophic gastritis in a region with high incidence of GC.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Ability and willingness to participate in the study and to sign and give informed consent * Biopsies were collected based on the recommendation of updated Sydney system Exclusion Criteria: * under 18 or over 80 years old * history of gastrectomy * severe systemic diseases or malignancy
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What it tests

  • Esophagogastroscopy (OLGA 0-Ⅰ)
  • Esophagogastroscopy (OLGA II)
  • Esophagogastroscopy (OLGA III-IV)
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Where

1 site
Renji Hospital, School of Medicine, Shanghai Jiao Tong University
Shanghai, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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